The prognostic value of KRAS mutation in patients with colorectal cancer liver metastases (CLM) receiving neoadjuvant chemotherapy following liver resection was investigated. The response rate to neoaduvant therapy was similar in patients with aKRAS mutation and those with the wild‐type gene. KRAS mutation had a negative prognostic effect on recurrence‐free survival.
Br J Surg 2012;99(11):1575-82
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